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SUMMARY:Computational Neuroscience Journal Club - Samuel Eckmann and Yasha
 r Ahmadian
DTSTART:20221108T140000Z
DTEND:20221108T160000Z
UID:TALK192569@talks.cam.ac.uk
CONTACT:Luke Johnston
DESCRIPTION:Please join us for our fortnightly journal club online via zoo
 m where two presenters will jointly present a topic together. The next top
 ic is ‘Molecular Memory Codes’ presented by Samuel Eckmann and Yashar 
 Ahmadian.\n\nZoom information: https://eng-cam.zoom.us/j/84204498431?pwd=U
 m1oU284b1YxWThObGw4ZU9XZitWdz09 Meeting ID: 842 0449 8431 Passcode: 684140
 \n\nSummary: The view that memories are stored in the brain as synaptic co
 nnections\, and that memories are formed through associative modification 
 of synapses\, is widely accepted in neuroscience. However\, this view has 
 been challenged on experimental and conceptual grounds. As an alternative\
 , it has been proposed that molecules within a neural cell body store memo
 ries and that biochemical manipulation of these molecules is the neural ba
 sis of memory formation. We will give a brief introduction to the concept 
 and history of synaptic memory storage and its criticisms. We will then co
 ver a recent preprint that presents a bayesian theory of memory storage an
 d manipulation\, incorporating synaptic and intracellular storage sites in
  a combined framework. Finally\, we will take a closer look at how RNA mig
 ht be utilised as a biological substrate for memory formation and recall.\
 n\nReferences: - The molecular memory code and synaptic plasticity: a synt
 hesis — Gershman\, arXiv\, 2022 - The Coding Question — Gallistel\, Tr
 ends in Cognitive Sciences\, 2017 - An RNA -based theory of natural univer
 sal computation — Akhlaghpour\, Journal of Theoretical Biology\, 2022
LOCATION:In Person (CBL Seminar Room) and Online on Zoom
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