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SUMMARY:Fluid mechanics and development of mosaic ciliated tissues - Franc
 esco Boselli\, University of Cambridge
DTSTART:20221117T123000Z
DTEND:20221117T133000Z
UID:TALK192593@talks.cam.ac.uk
CONTACT:Raymond E. Goldstein
DESCRIPTION:Eukaryotic cilia and flagella provide motility to microorganis
 ms\, but also direct fluid flow inside animals during development and in m
 ature physiology in areas from the reproductive system to the brain. The d
 iversity in the biological function of these systems is reflected in their
  spatial organisation\, which sets how cilia work as a collective.\n\nCili
 a are often grouped in sparsely distributed multiciliated cells (MCCs). We
  will address the fluid mechanics of this mosaic architecture in embryos o
 f the frog Xenopus laevis. By combining live imaging and mathematical mode
 lling we will show how cilia best shear the tissue at a finite but low are
 a coverage\, a result that mirrors findings for other sparse distributions
  such as cell receptors and leaf stomata.\n\nWe will also discuss the forc
 e applied by a bundle of cilia to the fluid and the cell\, and how this ma
 y contribute to the self-organisation of this tissue during development. 
LOCATION:MR15\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
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