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SUMMARY:Valentine’s Day for people with multiple sclerosis: promoting br
 ain repair through remyelination - Professor Alasdair Coles\, Department o
 f Clinical Neurosciences
DTSTART:20230214T160000Z
DTEND:20230214T170000Z
UID:TALK192920@talks.cam.ac.uk
CONTACT:Dr Dervila Glynn
DESCRIPTION:*Theme: Beyond the Neuron: Glia\, vascular and immune cells*\n
 \nCurrent disease-modifying therapies in multiple sclerosis are all focuse
 d on suppressing the inflammatory phase of the disease. This has been extr
 emely successful\, and it is doubtful that significantly more efficacious 
 anti-inflammatory treatments will be found. However\, it remains the case 
 that people with relapsing-remitting multiple sclerosis acquire disability
  on treatment\, and enter the secondary progressive phase. I argue that we
  now need treatments that prevent neuronal degeneration. The most promisin
 g approach is to prevent axons degenerating by remyelination. Since the di
 scovery that the adult brain contains stem cells which can remyelinate\, t
 he problem now is how to promote endogenous remyelination\, and how to kno
 w when we have achieved this! We have successfully identified one drug whi
 ch promotes remyelination but unfortunately it is too toxic for use in the
  clinic. So the hunt continues.\n\nRegister in advance for this meeting:\n
 https://us02web.zoom.us/meeting/register/tZEsdO6opzsoHd1rc6xYkdpcepyScjv8g
 0tY \n\nAfter registering\, you will receive a confirmation email containi
 ng information about joining the meeting.
LOCATION:Register on Zoom - link in abstract
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