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SUMMARY:X-ray and insitu transmission electron microscopy to study calcium
  phosphate nucleation from bioactive glass dissolution - Dr Richard Langfo
 rd\, Cavendish Laboratory\, University of Cambridge
DTSTART:20221214T140000Z
DTEND:20221214T150000Z
UID:TALK193172@talks.cam.ac.uk
CONTACT:Dr Mark Leadbeater
DESCRIPTION:<b>Abstract <br></b>\n\nOne way to treat dentine hypersensitiv
 ity\, the short\, sharp pain on drinking something hot or cold\, is to blo
 ck the exposed dentinal tubules. In some toothpastes this is achieved by u
 sing bioactive glass as one of the active components. On contact with the 
 saliva the bioactive glass undergoes dissolution and drives the formation 
 of hydroxyapatite like material that occludes the tubules. \n\nIn this tal
 k I will discuss the pink beam X-ray tomography and the insitu liquid cell
  (LC) TEM work we have been using to measure the depth of occlusion in the
  tubules and the mode of action of the bioactive glass within the toothpas
 tes. Using pink beam tomography enabled the nucleation/occlusion and disso
 lution process within the tubules\, at different time points\, to be studi
 ed and enabled over 2000 tubules to be measured. In the insitu LC work it 
 was possible to observe in real time the nucleation driven by the bioactiv
 e glass and the acid etching of the material occluding the dentinal tubule
 s. \n\n<b>About the speaker</b><br>\n\nDr Richard Langford runs the Cavend
 ish Electron Microscopy Suite. In addition to working and training users h
 is work involves developing imaging techniques and the application of focu
 sed ion beams for micro and nanoengineering.  Over the last 10 years a lar
 ge part of Richard’s research has been on bioactive glasses\, using a va
 riety of imaging techniques to study the mode of action of the glasses. \n
 \nRichard has received PhD in Electrical Engineering and Physics degree fr
 om the Imperial College London.\n\n!https://www.cape.eng.cam.ac.uk/sites/w
 ww.cape.eng.cam.ac.uk/files/styles/leading/public/richard_langford.png?ito
 k=KuZIneP7!\n
LOCATION:EEDB Seminar Room\, Electrical Engineering and Online (registrati
 on required)
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