BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Remodeling of Mitochondria during Microbial Infection - Dr Lena Pe
 rnas | MPI\, Cologne
DTSTART:20230405T140000Z
DTEND:20230405T150000Z
UID:TALK194434@talks.cam.ac.uk
CONTACT:Hannah Burns
DESCRIPTION:The rewiring of mitochondrial metabolism serves as an innate i
 mmune-type defense mechanism that restricts the growth of the human parasi
 te Toxoplasma gondii. We recently reported a previously undescribed struct
 ure we term SPOT (structure positive for outer mitochondrial membrane (OMM
 ) that emerges from the OMM during infection. We propose that Toxoplasma h
 ijacks the formation of SPOTs\, a cellular response to OMM import stress\,
  to counteract mitochondrial nutrient defense and promote its growth. Here
 \, I discuss the fate and function of these peculiar structures.
LOCATION:MRC MBU\, Level 7 Lecture Theatre\, The Keith Peters Building\, C
 B2 0XY
END:VEVENT
END:VCALENDAR