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SUMMARY:Mitochondria dynamics and metabolism regulate species-specific fea
 tures of human brain development - Professor Pierre Vanderhaeghen | VIB-KU
  Leuven Center for Brain &amp\; Disease Research\, Belgium
DTSTART:20231213T150000Z
DTEND:20231213T160000Z
UID:TALK194440@talks.cam.ac.uk
CONTACT:Lisa Arnold
DESCRIPTION:The human brain\, in particular the cerebral cortex\, has unde
 rgone rapid expansion and increased complexity during recent evolution.\n\
 nOne striking feature of human corticogenesis is that it is highly protrac
 ted in time\, from prenatal stages of neurogenesis (taking months instead 
 of days in the mouse)\, to postnatal stages of neuronal maturation and cir
 cuit formation (taking years instead of weeks in the mouse). This prolonge
 d development is thought to contribute in an important fashion to increase
 d cortical circuit complexity and plasticity\, but the underlying mechanis
 ms remain poorly understood.\n \nHere we will present data that indicate t
 hat species-specific mitochondria dynamics and metabolism contribute in an
  important fashion to control key fate transitions and set the tempo of hu
 man corticogenesis\, with interesting implications for human brain evoluti
 on and diseases.\n
LOCATION:MRC MBU\, Level 7 Lecture Theatre\, The Keith Peters Building\, C
 B2 0XY
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