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SUMMARY:Unraveling the molecular evolution of betalain-producing enzymes t
 o boost their industrial application  - Dr Alejandra Guerrero Rubio\, Broc
 kington Group\, Department of Plant Sciences
DTSTART:20230316T121500Z
DTEND:20230316T134500Z
UID:TALK194710@talks.cam.ac.uk
CONTACT:Kumari Billakurthi
DESCRIPTION:Betalains\, the pigments restricted to some plants within the 
 order Caryophyllales\, have gained great interest in the last decades due 
 to their properties as antioxidant\, antitumoral and anti-inflammatory com
 pounds but also due to their biosynthetic compounds pathway. Gene duplicat
 ions within the lineage of the key enzyme L-DOPA-extradiol-dioxygenase (DO
 DA) gave rise to enzymes with high dioxygenase activity\, via neofunctiona
 lization\, involved in the production of betalains. Additionally\, the con
 vergent evolution of betalains has recently been confirmed by analyses of 
 the evolution of the key enzyme DODA.\n\nThe reconstruction of these indep
 endent duplications within the different origins might help to understand 
 the different molecular changes that were decisive in this gain of functio
 n\, which may help to engineer these enzymes with higher efficiency in bet
 alains production and could be of great interest to food\, pharmaceutical 
 and cosmetics industries.\n
LOCATION:Online / Plant Sciences LLT for Department members only
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