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SUMMARY:Contour-based data assimilation in cardiac modeling: from principl
 es to challenges - Dr Philippe Moireau\, Inria and Ecole Polytechnique
DTSTART:20230125T130000Z
DTEND:20230125T140000Z
UID:TALK195862@talks.cam.ac.uk
CONTACT:Yuan Huang
DESCRIPTION:A major challenge associated with cardiac modelling is to use 
 the large amount of data available on the system to circumvent the lack of
  an absolute ground truth for modelling\, as each model should\, in fact\,
  becomes patient specific\, with possibly nonstandard conditions associate
 d with disease. Data assimilation\, originally used in the environmental s
 ciences\, has now found its way into the life sciences and\, in particular
 \, cardiac modeling and aim at registering a mathematical model over avail
 able data. In this talk\, we present a control-oriented data assimilation 
 strategy called observer theory in which data-driven feedback expressions 
 control the trajectory of the simulated system so that it pursues the real
  target trajectory and some parameters are jointly identified. The design 
 of the feedback clearly depends on the type of model considered - mechanic
 s\, reaction diffusion\, wave or transport systems - but is also closely r
 elated to the type of data considered. Unless we want to rely on approxima
 te post-processing of the data\, it is a major challenge to use the data a
 s they are essentially supplied\, which are mostly just images of the patt
 erns or shapes of the underlying physical quantities. We will show example
 s of such observer design when we have access only to the front propagatio
 n of the cardiac action potential or map only the shape of the myocardial 
 region that deforms during a heartbeat.\n\nThe seminar will be held in a h
 ybrid format. We strongly encourage you to participate in person at MR 12 
 \, Centre of Mathematical Sciences\, CB3 0WA . Althernatively you can join
  using the following Zoom link:\n\n*Join Zoom Meeting:* https://maths-cam-
 ac-uk.zoom.us/j/93331132587?pwd=MlpReFY3MVpyVThlSi85TmUzdTJxdz09
LOCATION:This seminar will be held in a hybrid format at MR 12\, Centre of
  Mathematical Sciences\, CB3 0WA. Alternatively you can also join with Zoo
 m (see abstract for Zoom link).
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