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SUMMARY:Building and Breaking the Neural Tube  - Clare Buckley (PDN\, Univ
 ersity of Cambridge) 
DTSTART:20230220T143000Z
DTEND:20230220T153000Z
UID:TALK195985@talks.cam.ac.uk
CONTACT:Elena Scarpa
DESCRIPTION:My lab investigates the morphogenesis of epithelial tubes duri
 ng development and disease. Broadly\, we want to know how epithelial tubes
  first polarise\, how they open (rather than close) and why they break dur
 ing disease. We are currently particularly interested in understanding the
  links between cell-cell adhesion\, actomyosin contractility and cellular 
 mechanics during secondary neurulation. To investigate these processes\, w
 e use high resolution imaging\, CRISPR and optogenetics approaches in vivo
 \, with the developing zebrafish neural tube and in vitro\, within multice
 llular mouse embryonic stem cell cultures.   
LOCATION:Online
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