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SUMMARY:Junctional Remodelling in Vascular Morphogenesis  - Maria Paraskev
 i Kotini (Biozentrum\, Basel Switzerland)
DTSTART:20230213T143000Z
DTEND:20230213T153000Z
UID:TALK195994@talks.cam.ac.uk
CONTACT:Elena Scarpa
DESCRIPTION:Blood vessel development is an early and crucial phenomenon as
 sociated with the growth and survival of a vertebrate embryo. Blood vessel
  morphogenesis is driven by coordinated endothelial cell behaviours\, whic
 h depend on dynamic cell-cell interactions. In this context\, remodelling 
 of endothelial cell-cell junctions promotes morphogenetic cellular events 
 while preserving vascular integrity. How these processes interact is poorl
 y understood. To gain a better understanding on cell junction dynamics we 
 use in vivo time-lapse imaging on transgenic zebrafish lines. This talk wi
 ll focus on how endothelial cell junctions deal with an expanding lumen du
 ring early vascular development and how junctional remodelling contributes
  to the observed variation in blood vessel architectures in the developing
  organs. \n\n 
LOCATION:Online
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