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SUMMARY:A flexible evolutionary toolkit for neural development - Dr Angeli
 ka Stollewerk (Queen Mary\, University of London)
DTSTART:20230517T120000Z
DTEND:20230517T130000Z
UID:TALK199219@talks.cam.ac.uk
CONTACT:Nadine Randel
DESCRIPTION:In all metazoans conserved genes regulate the formation of tis
 sues and organs. This raises the question of how a limited set of developm
 ental genes can support the evolution of diverse shapes. My lab’s work o
 n early neurogenesis in insects and other arthropods revealed that conserv
 ed genes form a flexible evolutionary toolkit supporting the emergence of 
 different morphological modules that can be combined in various ways to ge
 nerate variations in nervous system development. The flexibility of the to
 olkit is not only aided by evolutionary changes in the interactions of the
  genes but also by their pleiotropic functions. Interestingly\, the flexib
 ility of the gene networks does not only support evolutionary changes but 
 also the maintenance of essential parts such as the development of pioneer
  neurons that establish the axonal scaffold. I will present examples demon
 strating these concepts based on my lab’s studies of the evolution of th
 e central and peripheral nervous system of various arthropod groups and sp
 ecies.  
LOCATION:Part II Lecture Theatre\, Department of Zoology
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