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SUMMARY:Warwick-Lancaster global COVID-19 model - Ioana Bouros\, Universit
 y of Warwick
DTSTART:20230517T110000Z
DTEND:20230517T120000Z
UID:TALK200953@talks.cam.ac.uk
CONTACT:Dr Ciara Dangerfield
DESCRIPTION:As the world recovers from the acute phase of the Covid-19 pan
 demic\, a key issue is how to avert future large waves of hospitalisations
  and deaths driven by novel SARS-CoV-2 variants. Vaccination booster campa
 igns play an important role in maintaining the level of immunity in the po
 pulation and reducing the risk of severe outcomes in infected individuals.
 \nIn this talk\, we present research commissioned by the WHO SAGE Covid-19
  Working Group. We consider a wave of infections caused by a novel SARS-Co
 V-2 variant\, and investigate the effects of deploying booster vaccines ac
 cording to six different age-based prioritisation strategies. We use eight
  different exemplar countries from around the world as test cases\, chosen
  to cover a range of socioeconomic backgrounds. The aim is to identify whi
 ch vaccine targeting strategies are most beneficial in terms of reducing i
 nfection and severe outcomes of infection\, given a limited number of avai
 lable booster vaccines.\nThis work extends earlier research conducted when
  the level of both infection- and vaccination-derived immunity was lower t
 han it is now. In all countries considered\, we show that prioritising the
  eldest and most vulnerable individuals for booster vaccination first is e
 xpected to lead to the best public health outcomes (e.g. fewest deaths). A
 ssuming sufficient vaccine supply\, serology-informed booster vaccination 
 strategies are predicted to be of limited benefit compared to simply vacci
 nating the most vulnerable individuals in the population. We hope that thi
 s research is useful for guiding booster vaccination strategies in countri
 es worldwide.
LOCATION:Zoom
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