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SUMMARY:Epigenome Function: from molecular mechanisms to intergenerational
  inheritance  - Dr Jamie Hackett\; EMBL
DTSTART:20230627T123000Z
DTEND:20230627T133000Z
UID:TALK201235@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:Jamie Hackett is a group leader at the European Molecular Biol
 ogy Laboratory (EMBL)\, within the Epigenetics and Neurobiology unit in Ro
 me\, Italy. He obtained his PhD at the University of Edinburgh\, and compl
 eted postdoctoral training at the University of Cambridge\, UK\, under Pro
 f. Azim Surani. The Hackett group investigates the fundamental principles 
 of epigenetic regulation\, from molecular mechanisms to organismal respons
 es. They integrate environmental perturbations and precision (epi)genome e
 diting technologies to dissect the mechanisms by which normal or aberrant 
 chromatin states functionally participate in genome control and developmen
 tal programming. They also model the impact of induced epigenomic changes 
 on intergenerational health and disease susceptibility. \n\nKey questions 
 include: \nWhat is the regulatory function of distinct chromatin states ac
 ross genomic contexts? How does normal or altered epigenome programming im
 pact development? How does the environment influence intergenerationally h
 eritable factors in germ cells?\n
LOCATION:King's Hedges Room\, Babraham Research Campus
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