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SUMMARY:Modelling Microtube Driven Invasion of Glioma - Thomas Hillen (Uni
 versity of Alberta)
DTSTART:20230823T100000Z
DTEND:20230823T110000Z
UID:TALK203590@talks.cam.ac.uk
DESCRIPTION:Malignant gliomas are highly invasive brain tumors. Recent att
 ention has focused on their capacity for network-driven invasion\, whereby
  mitotic events can be followed by the migration of nuclei along long thin
  cellular protrusions\, termed tumour microtubes (TM).&nbsp\; Here I devel
 op a mathematical model that describes this microtube-driven invasion of g
 liomas. I show that scaling limits lead to well known glioma models as spe
 cial cases such as go-or-grow models\, the PI model of Swanson\, and the a
 nisotropic model of Swan.&nbsp\;Numerical simulations are used to compare 
 between the models. (Joint work with N. Loy\, K.J. Painter\, R. Thiessen).
  
LOCATION:Seminar Room 2\, Newton Institute
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