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SUMMARY:Original Curve: Reshaping of archaeal cells - Andela Saric (IST Au
 stria)
DTSTART:20230906T080000Z
DTEND:20230906T084000Z
UID:TALK203839@talks.cam.ac.uk
DESCRIPTION:Eukaryotic cells likely arose from the symbiosis of an archaea
 l and an (alphaproteo)bacterial cell. The archaeal host gave rise to the e
 ukaryotic cell body\, including the plasma membrane\, and the associated p
 roteobacteria went on to become mitochondria. Because of this\, the nanosc
 ale machinery that performs reshaping of eukaryotic membranes likely origi
 nates in archaea.&nbsp\;Today I will discuss physical modelling of archaea
 l membrane reshaping\, focusing on cell division via ESCRT-III machinery\,
  in comparison with live cell data\, and membrane trafficking. In particul
 ar\, archaeal membranes are known to be dramatically different from eukary
 otic and bacterial membranes: they are built out of bolalipids &mdash\; li
 pids with two heads connected with one tail &mdash\; organised into monola
 yers rather than bilayers. I will discuss the implication of this monolaye
 r organisation on mechanical properties of archaeal membranes\, their resh
 aping\, and ability to sustain extreme environmental conditions.
LOCATION:Seminar Room 1\, Newton Institute
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