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SUMMARY:UK Biobank: new insights into metabolomics and coronary heart dise
 ase risk /// democratising access to large scale genomic and phenotypic da
 ta for discovery science - Ben Lacey (University of Oxford) and Danyao Jin
  (University of Oxford)
DTSTART:20230907T123000Z
DTEND:20230907T133000Z
UID:TALK204541@talks.cam.ac.uk
CONTACT:Spencer Keene
DESCRIPTION:With its unique combination of scale\, depth\, maturity and ac
 cessibility\, UK Biobank is enabling researchers worldwide to perform inno
 vative health-related research. This talk will provide key information abo
 ut this landmark study\, highlight recent and future enhancements to the r
 esource\, and new ways in which it is democratising access via the new clo
 ud-based Research Analysis Platform. The value of the resource will be ill
 ustrated by several examples\, with particular reference to recent work us
 ing metabolomics data to better understanding the associations of lipids\,
  lipoproteins and other factors with risk of coronary heart disease.\n\nUK
  Biobank is a prospective cohort study of 500\,000 people that has integra
 ted large-scale genomic data (in all participants) and deep phenotyping da
 ta (including lifestyle factors\, physical measures and multi-modal imagin
 g) with long-term follow-up of health outcomes through linkage to electron
 ic health records. The recent addition of detailed genomic sequencing data
  plus large-scale metabolomic and proteomic data has created an even more 
 powerful resource\, which will enable a better understanding of disease bi
 ology and will support innovative drug development for more effective ther
 apies. Ready access to this combination of in-depth genomic\, imaging\, an
 d other health information from 500\,000 UK Biobank participants is enabli
 ng researchers worldwide to advance discovery science and improve human he
 alth.
LOCATION:Heart and Lung Research Institute (ground floor) or Virtually via
  Zoom
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