BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Physical principles of controlling condensates by reactions - Davi
 d Zwicker (Max Planck Institute for Dynamics and Self Organisation)
DTSTART:20231012T092000Z
DTEND:20231012T100000Z
UID:TALK204904@talks.cam.ac.uk
DESCRIPTION:Condensates spatially partition the complex cellular interior 
 using genetically encoded interactions between various biomolecules. Yet\,
  to fulfill countless cellular functions\, condensates also need to form a
 t the right time\, at the right position\, and with the right size. I will
  demonstrate how driven chemical reactions enable such control. Based on t
 hermodynamic constraints\, I will show that reactions involving the drople
 t material must be driven out of equilibrium\, e.g.\, by consuming ATP. Th
 en\, enzymes concentrated inside or outside the droplet can create composi
 tional gradients that affect droplet nucleation\, shape\, and position. In
 terestingly\, the length scale associated with this reaction-diffusion sys
 tem governs droplet size and spacing\, akin to Turing patterns. I will mak
 e this analogy more precise by discussing Turing patterns with physical in
 teractions\, i.e.\, non-ideal diffusion. In summary\, I will discuss the i
 ntertwined physics of non-ideal diffusion and chemical reactions\, which i
 s relevant beyond Biology.
LOCATION:Seminar Room 1\, Newton Institute
END:VEVENT
END:VCALENDAR