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SUMMARY:Chasing the ghost behind germination and starvation: the unidentif
 ied hormone ‘KL’ - Dr Thomas Irving\, Cereal Symbiosis Group\, Crop Sc
 ience Centre\, Department of Plant Sciences.
DTSTART:20231109T121500Z
DTEND:20231109T134500Z
UID:TALK206311@talks.cam.ac.uk
CONTACT:116479
DESCRIPTION:KAI2-Ligand (KL) is a putative plant hormone of unknown chemic
 al identity. It acts through a receptor KAI2/D14L\, present throughout the
  green linage\, to degrade repressor proteins (SMAXs)\, and impacts germin
 ation\, nutrient sensing\, and a wide range of developmental processes. Th
 e Paszkowski lab has shown that rice D14L is utterly essential for the pla
 nt to interact with arbuscular mycorrhizal fungi. \nI will discuss our att
 empts to elucidate how KL promotes mycorrhizal colonisation and integrates
  nutrient and light signalling. I have produced a suite of protein biosens
 ors to monitor KL signalling as part of the ENSA collaboration\, as we att
 empt to bring this knowledge into practical use to maintain the benefits o
 f the symbiosis in the field under nonpermissive fertilisation. I take a d
 rug discovery approach\; screening small molecules for D14L agonism with a
 n in vitro FRET assay\, then assessing protein turnover in planta with a 
 ‘degron’ sensor. \n
LOCATION:Large Lecture Theatre\, Department of Plant Sciences
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