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SUMMARY:Therapeutic Drug Monitoring in Neuropsychopharmacology - Dr Georgi
 os Schoretsanitis\, Department of Psychiatry\, Psychotherapy and Psychosom
 atics\, Hospital of Psychiatry\, University of Zurich\, Zurich\, Switzerla
 nd. Assistant Professor\, The Donald and Barbara Zucker School of Medicine
  at Hofstra/Northwell\, NY\, USA.
DTSTART:20231123T123000Z
DTEND:20231123T133000Z
UID:TALK207439@talks.cam.ac.uk
CONTACT:Nikolina Skandali
DESCRIPTION:Real-world data suggest very low treatment response rates in c
 linical routine. The search for treatment personalization tools and potent
 ial moderators of clinical outcomes is ongoing. Therapeutic Drug Monitorin
 g (TDM)\, i.e. the quantification of drug concentrations in plasma or seru
 m to titrate the individual dose\, is currently the only established perso
 nalized medicine tool. Analyzing large TDM datasets acquired as part of cl
 inical practice can help addressing common clinical questions deriving fro
 m common clinical scenarios. This type of questions frequently refer to th
 e treatment of particularly vulnerable patient subgroups\, where different
  patterns of drug disposition are expected. For example\, the mental healt
 hcare of women in pregnancy or lactation can comprise a challenge for prof
 essionals involved including prescription of pharmacological agents. We us
 e different types of data to understand the risk of mental distress in wom
 en during pregnancy and at postpartum\, while we also focus on exposure of
  fetuses/newborns to pharmacotherapy prescribed to the mothers during preg
 nancy and lactation. Moreover\, we are interested in understanding moderat
 ors of effectiveness and safety outcomes for well-established psychiatric 
 therapies\, including electroconvulsive therapy and psychotherapies.
LOCATION:https://cam-ac-uk.zoom.us/j/6245857987?pwd=WS9QWWxCTXU0ZXFvcUpzU2
 E2SkRyZz09
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