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SUMMARY:Revolutionizing Biosensing Technologies: Plug and Play Devices in 
 Medical and Agricultural Diagnostics  - Muhammad J. A. Shiddiky\, Rural He
 alth Research Institute (RHRI)\, Charles Sturt University\, Orange NSW 280
 0
DTSTART:20231024T160000Z
DTEND:20231024T170000Z
UID:TALK207643@talks.cam.ac.uk
CONTACT:Pietro Lio
DESCRIPTION:Abstract\n\nThe availability of simple\, rapid\, and inexpensi
 ve methods\, along with plug-and-play devices that can diagnose and treat 
 diseases at their early stages on-site\, has the potential to transform bi
 omedical and agricultural disease diagnosis. This transformation would shi
 ft the current disease-centric system to a more personalized\, predictive\
 , and preventative model\, focused on disease prevention and management. I
 n addition to improving overall diagnosis and disease management strategie
 s\, the plug-and-play test would also be particularly valuable in remote l
 ocations\, such as rural communities (i.e.\, Aboriginal and Torres Strait 
 Islander people)\, military units\, and remote farms and agricultural fiel
 ds. Current diagnostic methods for biomedical and agricultural application
 s often require expensive materials and laborious procedures\, as well as 
 sophisticated instrumentation and facilities. As a result\, they are not w
 idely accessible in rural communities\, developing countries\, or other re
 source-poor settings.\n\nThe emergence of magnetic nanomaterials that func
 tion as both 'dispersible capture agents' and 'nanoenzymes' with peroxidas
 e-like activity has been instrumental in the development of more affordabl
 e\, on-site diagnostic methods and devices. In recent years\, our team has
  developed several methods and devices utilizing a series of nano-architec
 ted magnetic nanomaterials\, 3D printing technology\, advanced engineering
 \, and alternating current (AC)-induced fluid manipulation in purpose-buil
 t microfluidic devices. We have used these tools to achieve 'plug-and-play
 ' analysis of many biomedical biomarkers\, such as circulating cancer biom
 arkers like CTCs\, exosomes\, RNAs\, cell-free DNA (cf-DNA)\, circulating 
 tumor DNA (ct-DNA)\, agricultural biomarkers such as plant disease causati
 ve pathogens and their corresponding nucleic acid sequences\, and global w
 ater-related disease (i.e.\, cryptosporidiosis\, giardiasis) biomarkers. I
 n this presentation\, I will discuss some of these developments\, highligh
 ting the applications of a few new handheld devices in these areas.\n\nBio
 \n\nProfessor Shiddiky is a Distinguished Professor of Nanotechnology at t
 he Rural Health Research Institute (RHRI) at Charles Sturt University (Ora
 nge Campus)\, NSW\, Australia. He obtained his PhD in 2007 and subsequentl
 y held positions as a Postdoctoral Research Fellow at Monash University\, 
 an ARC DECRA Fellow at the University of Queensland\, an NHMRC Career Deve
 lopment Fellow\, and an Associate Professor at Griffith University. He is 
 a global leader in the fields of analytical chemistry\, sensor technology\
 , and nanobiotechnology\, specializing in developing biosensing methods an
 d portable diagnostic devices for various biomedical and agricultural appl
 ications. He leads an ambitious research program at RHRI aimed at developi
 ng point-of-care/on-site diagnostic devices and technologies for early det
 ection and management of diseases from concept through to commercializatio
 n. His work is highly translational and has resulted in multiple licensed 
 IPs\, several industrial collaborations\, and commercial research contract
 s. Additionally\, his research has laid the foundation for two global biot
 ech start-up companies by providing critical background IPs. Prof Shiddiky
  has a career total of 180 publications\, with over 9000 citations (h-inde
 x = 58). The average citation rate of his publications is 49+ citations pe
 r article. He serves as a member of the Editorial Board/Editorial Advisory
  Board in several top-quality journals\, including Analytical Chemistry (A
 CS)\, Scientific Reports (Springer Nature)\, and Analyst (RSC)
LOCATION:Lecture Theatre 2\, Computer Laboratory\, William Gates Building
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