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SUMMARY:Mathematical modelling to develop insights into cancer evolution -
  Dr Weini Huang
DTSTART:20240307T160000Z
DTEND:20240307T170000Z
UID:TALK209002@talks.cam.ac.uk
CONTACT:Samantha Noel
DESCRIPTION:Many diseases in human including cancers\, are caused by genet
 ic alternations and errors starting from a single cell. The origin of thes
 e genetic errors and the expansion of the abnormal cells carrying these ge
 netic errors are often stochastic processes. Here I use different projects
  from modelling liver stem cell niche\, clonal fitness in Leukemia\, pre-e
 xisting resistant in colon cancers to extra-chromosomal DNA\, to explain h
 ow we apply stochastic processes to understand cancer dynamics. I will use
  these examples to summarise key steps working with projects in mathematic
 al oncology and demonstrate the importance of integrating mechanistic mode
 l with experimental or clinical data on a better understanding of cancer e
 volution.\n
LOCATION:Biffen Lecture Theatre\, Department of Genetics\, Downing Site
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