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SUMMARY:Mechanical force guided cell migration in early embryonic developm
 ent - Lakshmi Balasubramaniam
DTSTART:20240222T183000Z
DTEND:20240222T192000Z
UID:TALK209440@talks.cam.ac.uk
CONTACT:Igor Kavrakov
DESCRIPTION:Chicken embryo development occurs through the transformation o
 f a circular blastodisc into an anisotropically shaped body axis with diff
 erent organs such as the brain\, spinal cord that form the axis along with
  heart and the blood vessel network. This shape transformation is known to
  be mediated through mechanical forces and interaction between the differe
 nt tissue layers. One major tissue during avian development called the ext
 ra embryonic tissue gives rise to the blood circulation network and is a p
 oorly studied tissue. While cells in this region are migratory and grow du
 ring development\, not much is known about how their migratory properties 
 affect adjacent tissues that give rise to the brain and body axis. In this
  talk\, I will describe how our work has characterized the mechanical prop
 erties of this region with potential implications to study birth defects s
 uch as spina bifida.
LOCATION:Richard King room\, Darwin College
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