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SUMMARY:PDRA Talks: Nuclear envelope integrity in health and disease | A r
 ole for the proton - Dr Anne Janssen\, Dr Luke Pattison\, University of Ca
 mbridge\, Department of Pharmacology
DTSTART:20240308T160000Z
DTEND:20240308T170000Z
UID:TALK210367@talks.cam.ac.uk
CONTACT:Daniel Paolo Juan
DESCRIPTION:Nuclear envelope integrity in health and disease\n\nDr Anne Ja
 nssen\n\nUniversity of Cambridge\, Department of Pharmacology\n\nBiography
 \n\nAnne studied Biotechnology at Wageningen University. After finishing h
 er Masters degree she started her PhD in the lab of\nLukas Kapitein (Utrec
 ht University\, the Netherlands) working on the generation of inducible to
 ols to study protein aggregation and degradation by the autophagy pathway.
  During her PhD work she got interested in the nuclear envelope which is w
 hy she joined the lab of Delphine Larrieu in 2019 to work on nuclear envel
 ope integrity and premature aging diseases. Initially at CIMR\, the lab mo
 ved to the department of Pharmacology in 2022. Currently\, Anne works on a
 n independent project for which she got a Leverhulme Early Career Fellowsh
 ip to discover new players in nuclear envelope integrity maintenance.\n\nD
 r Luke Pattison\n\nA role for the proton-sensing GPCR\, GPR65 in inflammat
 ory joint pain\n\nUniversity of Cambridge\, Department of Pharmacology\n\n
 Biography\n\nLuke studied Molecular and Cellular Biology at the University
  of Bath. During his undergraduate degree he undertook a\nplacement at the
  Monash Institute of Pharmaceutical Sciences in Melbourne\, Australia\, wh
 ere he studied the compartmentalised signalling of a G protein-coupled rec
 eptor (GPCR) implicated in inflammatory pain. Luke undertook his\ndoctoral
  research in the Smith lab\, submitting his thesis in 2021\, which explore
 d the contributions of proton-sensing GPCRs to inflammatory pain. Luke is 
 continuing in the Smith lab as a postdoctoral researcher working on the Ad
 vanced Discovery of\nVisceral Analgesics via Neuroimmune Targets and the G
 enetics of Extreme human phenotypes (ADVANTAGE) consortium as part\nof the
  MRC Advanced Pain Discovery Platform.\n\nVenue: Level 2 Seminar Room\n\nZ
 oom Link: https://cam-ac-uk.zoom.us/j/89184640892?pwd=VnZXbEU4bDdtbkt5MEV2
 NWt0RUJtUT09\n\nMeeting ID: 891 8464 0892\n\nPasscode: 620598
LOCATION:Seminar Room (Level 2)\, Dept of Pharmacology 
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