BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Motility-induced patterning in signalling bacteria - Wesley Ridgwa
 y\, University of Oxford
DTSTART:20240208T130000Z
DTEND:20240208T140000Z
UID:TALK211852@talks.cam.ac.uk
CONTACT:Lloyd Fung
DESCRIPTION:Chemical signaling\, or quorum sensing (QS)\, promotes a varie
 ty of collective behaviours in bacteria\, from biofilm formation to swarmi
 ng. In principle\, QS systems can be coupled with genes controlling motili
 ty to enable bacteria to self-organise into tunable spatio-temporal patter
 ns. However\, it is not well-understood in general how gene-regulatory net
 works in individual cells affect population-level patterning.\n\n\nIn this
  talk\, we will investigate the role of the gene-regulatory network on eme
 rgent patterning in a population of motile bacteria that interact via QS. 
 I will present a multiscale continuum model that explicitly accounts for g
 enetic regulation of motility and signal production through chemical struc
 turing. Using a WKBJ-like framework in the limit of small noise in the gen
 e-regulatory network\, we derive criteria for the onset of two types of em
 ergent patterning. Crucially\, we also uncover a new route to the well-kno
 wn phenomenon of motility-induced phase separation (MIPS) through the gene
 tic regulation of tumbling frequency. Lastly\, I will briefly discuss rece
 nt progress that extends this work to growing populations and more complic
 ated gene-regulatory kinetics that possess multiple steady-states or limit
  cycles.\n\n
LOCATION:MR15\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
END:VEVENT
END:VCALENDAR