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SUMMARY:3D modelling of intracellular active fibre networks for understand
 ing plant development - Tamsin Spelman
DTSTART:20240509T120000Z
DTEND:20240509T130000Z
UID:TALK212116@talks.cam.ac.uk
CONTACT:Marco Vona
DESCRIPTION:All Eukaryotic cells\, including those that make up our own bo
 dies\, have a dynamic and active fibre network known as the cytoskeleton w
 hich plays a crucial role in many cellular functions\, including structura
 l support and organelle transport. The arrangement of these fibres is esse
 ntial for facilitating directional cell growth to create the diverse cell 
 shapes necessary for the function of the organism e.g. elongated cells nee
 ded for plant stems.  In this talk I will discuss the interplay between ce
 ll geometry and the cytoskeleton in 3D focussing on the plant root hair ce
 ll. \nThe root hair cell is a long\, thin single cell which grows off the 
 edge of the plant root. First\, we will consider how cell shape directly e
 ffects cytoskeleton alignment using our 3D cytoskeleton computational mode
 l. We will also consider the opposite where cytoskeleton fibres are create
 d and grow completely freely in 3D space\, comparing our simulations to ou
 r 3D mathematical mean field theory model. Within the root hair\, we will 
 then consider the patterns of cytoskeleton density and link this to nucleu
 s motion and root hair cell shape to develop a model of the growing root h
 air. We'll explore the effect of various factors on the root hair such as 
 maturation\, drug treatments causing cytoskeleton perturbations\, and grow
 th in media of various stiffnesses.  
LOCATION:MR15\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
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