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SUMMARY:Exploring microcircuit properties for memory\, from rodents to the
  human brain - Jake Watson\, IST Austria (Klosterneuburg AT)
DTSTART:20240222T153000Z
DTEND:20240222T163000Z
UID:TALK212650@talks.cam.ac.uk
CONTACT:Ingo Greger
DESCRIPTION:Human brain function arises from a continuous activity\nflowin
 g through specific cells\, guided by intricate synaptic arrangements. Ther
 efore\, determining the architecture and properties of functioning microci
 rcuits is crucial for understanding the complexities of brain function. Ho
 wever\, our current microcircuit knowledge is limited\, and for the human 
 brain – almost non-existent. I will present our recent findings using a 
 combination of multicellular patch-clamp-based circuit analysis and super-
 resolution imaging to elucidate the microcircuit architecture of the hippo
 campus\, a critical brain region for memory. Studying the rodent brain at 
 the individual cell level reveals distinct cell populations with unique pr
 operties and interconnectivity\, which significantly enhance the computati
 onal capabilities. Furthermore\, I will discuss how we apply these techniq
 ues to the human brain\, exploring the black box of our own wiring\, which
  reveals new insights into the circuit basis of memory storage.
LOCATION:Klug Seminar Room\, Level 2\, LMB
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