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SUMMARY:Neurotransmitter receptor gradients: gateways for subcortical rout
 ing of cortex-wide dynamics during cognition - Seán Froudist-Walsh\, U Br
 istol
DTSTART:20240319T100000Z
DTEND:20240319T110000Z
UID:TALK213382@talks.cam.ac.uk
CONTACT:Guillaume Hennequin
DESCRIPTION:Recent advances in connectomics and neurophysiology make it po
 ssible to probe whole-brain mechanisms of cognition and behavior. However\
 , as yet\, few models in computational neuroscience have tackled the mecha
 nisms underlying highly distributed neural activity during cognition. In t
 his talk I will describe our anatomy-led approach to developing cortex-wid
 e models of neural dynamics during cognitive tasks and our recent anatomic
 al findings of graded expression of neurotransmitter receptors in the cort
 ex.  I will highlight our investigations into how inputs from the thalamus
  and neuromodulatory systems may shift the cortical dynamical landscape\, 
 and how this may confer flexibility on distributed cognitive functions suc
 h as conscious perception and working memory.
LOCATION:CBL Seminar Room\, Engineering Department\, 4th floor Baker build
 ing
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