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SUMMARY:Keynote speaker - Building the Virtual Human Twin: from an engaged
  ecosystem to an incipient infrastructure - Liesbet Geris (Université de 
 Liege)
DTSTART:20240603T090000Z
DTEND:20240603T100000Z
UID:TALK214450@talks.cam.ac.uk
DESCRIPTION:Following the definition of the European Commission\, a Virtua
 l -Human Twin (VHT) is a digital representation of a human health or disea
 se state. VHTs refer to different levels of human anatomy (e.g. cells\, ti
 ssues\, organs or organ systems). They are built using software models and
  data and are designed to mimic and predict behaviour of their physical co
 unterparts\, including interaction with additional diseases a person may h
 ave. The key potential in health and care of this technology is related to
  targeted prevention\, tailored clinical pathways\, and to supporting heal
 thcare professionals in virtual environments. Examples include implementat
 ion of clinical trials for medicines and devices\, medical training\, surg
 ical intervention planning\, and several other potential use cases in virt
 ual world environments. A public VHT infrastructure is the subject of an o
 pen tender. This infrastructure should enable the pooling of resources and
  assets (data\, models\, algorithms\, computing power\, storage etc.) to d
 evelop these twins in healthcare and assess their credibility. Hence\, it 
 should entail the development of a federated public infrastructure and the
  collection of said resources\, driven by the engagement of a collaborativ
 e ecosystem.\nIn order to realise the potential of the VHT\, a shared visi
 on and inclusive eco-system driven roadmap is being developed\, supported 
 through the EDITH Coordination and Support Action. The roadmap contains a 
 blueprint of the Virtual Human Twin and&nbsp\; will identify the required 
 (technical) developments\, including but not limited to interoperability\,
 &nbsp\; computability\, hardware and integration of health models & data. 
 Ethical\, Legal and Social elements are discussed\, including privacy\, in
 tellectual property rights\, standards\, regulations\, ethics and social a
 cceptance. The user perspective is developed for a range of stakeholders\,
  whose needs and value propositions have been identified through a range o
 f activities and interactions. Finally\, sustainability of the ecosystem a
 nd infrastructure are examined\, looking at incorporation in clinical and 
 industrial workflow\, development of economic activities\, a member-state 
 strategy and the creation of a public research infrastructure organisation
 . &nbsp\;After&nbsp\; going through extensive review by the ecosystem\, th
 e first draft of the roadmap&nbsp\; has been released (https://doi.org/10.
 5281/zenodo.8200955) and is open for additions and comments (http://www.ed
 ith-csa.eu/roadmap). Current activities focus on the drafting of clear rec
 ommendations and outlining a strategic plan for the further development of
  the VHT\, to be discussed with the entire ecosystem during the upcoming m
 eeting in Amsterdam (https://www.aanmelder.nl/edith-csa-ecosystem-meeting/
 home).&nbsp\;&nbsp\; &nbsp\;&nbsp\;
LOCATION:Seminar Room 1\, Newton Institute
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