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SUMMARY:LMB Seminar: Identification of alternative pathways for metabolism
  or cell death using haploid genetics - Thijn Brummelkamp\, Netherlands Ca
 ncer Institute/Oncode Institute
DTSTART:20240603T100000Z
DTEND:20240603T110000Z
UID:TALK216967@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Human genes act together in complex networks to perform a myri
 ad of functions. Whereas details maps exist for most biochemical pathways\
 , the wiring of genetic networks in human cells is poorly understood. Usin
 g genetics in haploid human cells we have assigned genes to more than a hu
 ndred quantitative cellular phenotypes.This approach enables us to identif
 y missing enzymes in cell biology\, alternative metabolic routes and a pat
 hway that activates cell death in response to cancer therapeutics. 
LOCATION:In person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoo
 m\, link:https://mrc-lmb-cam-ac-uk.zoom.us/j/95178919042?pwd=OUp6RUN3a0dkN
 FZqWGxQV0p0T0JOZz09
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