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SUMMARY:Devil Facial Tumour Disease: MHC genetics of a contagious cancer -
  Dr Hannah Siddle\, Department of Pathology\, University of Cambridge
DTSTART:20091217T163000Z
DTEND:20091217T173000Z
UID:TALK21735@talks.cam.ac.uk
CONTACT:Suzy Blows
DESCRIPTION:Tasmanian devils face extinction due to the emergence of a con
 tagious cancer\, Devil Facial Tumour Disease (DFTD).  DFTD is a clonal can
 cer that has spread through the devil population by biting.  The disease i
 s highly unusual as it is not just a tumour but also a tissue graft\, pass
 ed between individuals without invoking an immune response.  Major Histoco
 mpatibility Complex (MHC) molecules play a key role in immune responses to
  both tumours and grafts.  This talk will discuss the role that MHC genes 
 have played in allowing  the invading cell line to spread so rapidly throu
 gh the population and strategies for conserving Tasmanian devils in the wi
 ld.
LOCATION:Lecture Theatre 1\, Department of Veterinary Medicine
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