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SUMMARY:Measuring the timing and noise of bacteriophage infection steps - 
 Charlie Wedd\, University of Cambridge
DTSTART:20240613T130000Z
DTEND:20240613T140000Z
UID:TALK217924@talks.cam.ac.uk
CONTACT:Fulvio Forni
DESCRIPTION:Bacteriophages are viruses which infect bacteria. A bacterioph
 age will begin its life cycle by injecting a single molecule of DNA into a
  host cell\, before shutting down the host\, taking control of the host’
 s resources\, making copies itself\, and bursting open the host cell – a
 ll in just 17 minutes. In this talk\, I will give a brief introduction to 
 bacteriophage biology\, before explaining how we have experimentally measu
 red the timing of some of these infection steps in our lab. We will then r
 eflect on how the bacteriophage controls and coordinates these steps to pr
 oduce a successful infection. Some considerations include the role of smal
 l copy number noise\, and how the timing of bacteriophage genes expression
  is controlled despite the apparent scarcity of regulatory elements in the
  bacteriophage genome. Lastly\, I will discuss how variability in infectio
 n outcomes across a population of bacteriophages may influence the fitness
  of the population as a whole.\n\nThe seminar will be held in LR5\, Baker 
 Building\, Department of Engineering\, and online (zoom): https://newnham.
 zoom.us/j/92544958528?pwd=YS9PcGRnbXBOcStBdStNb3E0SHN1UT09
LOCATION:JDB Seminar Room\, Department of Engineering and online (Zoom)
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