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SUMMARY:Evaporation dynamics of respiratory-like droplets and their implic
 ations on virus infectivity - Javier Rodríguez Rodríguez\, Carlos III Un
 iversity of Madrid
DTSTART:20240701T123000Z
DTEND:20240701T133000Z
UID:TALK218278@talks.cam.ac.uk
CONTACT:Professor Grae Worster
DESCRIPTION:Viruses can remain infective in the aerosolized solid residue 
 left upon the evaporation of respiratory droplets for very long times. How
 ever\, the precise mechanisms that allow viral particles to endure the har
 sh physico-chemical conditions found in these drops for so long are poorly
  understood. In this talk we present our ongoing theoretical and experimen
 tal study of the transport of solutes and viral particles inside evaporati
 ng complex drops\, with the aim at elucidating the precise physico-chemica
 l mechanisms that ultimately lead to viral inactivation. In a first part o
 f the talk we present a model of the evaporation of complex drops\, contai
 ning water\, salt\, and a glycoprotein (Mucin). This model has been valida
 ted against experiments of evaporating spherical droplets semi-levitated o
 n superhydrophobic substrates\, as well as sessile ones. This model is the
 n used to estimate the viral decay rate depending on the drop properties a
 nd atmospheric conditions. In a second part of the talk\, we develop a mor
 e comprehensive model of the transport of salt and protein inside the drop
 . We use this model to explain the spatial distribution of viral particles
  in the dry residue of a sessile drop that we have observed experimentally
 . We conclude with a discussion of the plausible mechanisms of viral inact
 ivation\, based on our experiments.
LOCATION:MR13
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