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SUMMARY:T cell responses to EBV: viral evasion\, antigen immunodominance a
 nd priming - Professor Alan Rickinson\, University of Birmingham
DTSTART:20100203T123000Z
DTEND:20100203T133000Z
UID:TALK21901@talks.cam.ac.uk
CONTACT:Prof. Jim Kaufman
DESCRIPTION:Our work focuses on Epstein-Barr virus (EBV)\, a human gamma-h
 erpesvirus with B cell growth-transforming ability that is the causative a
 gent of a self-limiting lymphoproliferative disease\, infectious mononucle
 osis\, and is aetiologically linked to a range of lymphoid and epithelial 
 malignancies.  \n\nBesides studying these disease associations\, our more 
 basic interests include the mechanisms of EBV persistence and immune evasi
 on in the immune host. The seminar will cover the basic immunology of EBV 
 infection\, including recent work on antigen choice for CD4 and CD8 T cell
  responses and the effect of immune evasion on that choice.
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis Court Road
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