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SUMMARY:The role of natural killer cells in MS - Professor Danny Altmann\,
  Imperial College\, London
DTSTART:20100224T123000Z
DTEND:20100224T133000Z
UID:TALK21905@talks.cam.ac.uk
CONTACT:Prof. Jim Kaufman
DESCRIPTION:Danny Altmann is in the Department of Medicine at Imperial Col
 lege where he is Director of Research Strategy. His lab have for many year
 s used a combination of human\, clinical studies and ‘humanised’ trans
 genic approaches to investigate pMHC/TCR interactions in infectious and au
 toimmune disease. Currently\, half of his lab is devoted to studies of T c
 ell and NK cell responses in multiple sclerosis\, while the remainder work
  on the T cell immunology of bacterial sepsis\, particularly strep\, anthr
 ax and burkholderia.\n\nRecent publications include:\n\n•	Campbell JD et
  al.\,  (2009). Peptide immunotherapy in allergic asthma generates IL-10-d
 ependent immunological tolerance associated with linked epitope suppressio
 n.  J Exp Med. 206(7):1535-47\n \n•	Kaushansky N et al.\, (2009). HLA-DQ
 B1 0602 determines disease susceptibility in a new "humanized" multiple sc
 lerosis model in HLA-DR15 (DRB1 1501\; DQB1 0602) transgenic mice. J Immun
 ol. 183(5):3531-41. \n\n•	Reynolds C\,  et al.\,  (2009). Natural killer
  T cells in bronchial biopsies from human allergen challenge model of alle
 rgic asthma. J Allergy Clin Immunol. 124(4):860-2 \n\n•	Ingram\, R.J et 
 al.\,  2010. Natural exposure to cutaneous anthrax gives long-lasting T ce
 ll immunity encompassing infection-specific epitopes. J. Immunol\, in pres
 s\n
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis Court Road
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