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SUMMARY:Pararetroviruses (EPRV)-Derived 22nt sRNAs &amp\; Their Role In DI
 CER2-Mediated Viral Immunity In Tomato Hybrids - Pei Qin -Sabrina- Ng (Bau
 lcombe Lab Group\, DPS)
DTSTART:20241128T121500Z
DTEND:20241128T134500Z
UID:TALK219961@talks.cam.ac.uk
CONTACT:115405
DESCRIPTION:*Abstract* DICER2-dependent 22nt small RNAs are essential in p
 lant antiviral defence through RNA silencing. These RNAs\, derived from so
 urces such as transposable elements like endogenous pararetroviruses (EPRV
 s)\, are pivotal in enhancing plant immunity. EPRVs\, integrated into plan
 t genomes from past infections\, act as an "infection memory\," improving 
 resistance to pararetroviruses. Our recent study shows that EPRV-derived s
 mall RNAs (sRNAs) are activated in tomato hybrids\, with an enrichment of 
 22nt sRNAs produced via the DICER2 (DCL2) biogenesis pathway. However\, th
 e specific role of DICER2-dependent 22nt sRNAs remains underexplored. We e
 xamined the EPRV-derived 22nt sRNAs in both wild-type and dcl2 tomato muta
 nts to elucidate the role of these DCL2-dependent 22nt sRNAs in plant immu
 nity\, especially concerning hybrid vigour. Utilizing the long-read tomato
  genome and bioinformatics\, we analysed regions across four EPRV subtypes
  where 22nt sRNAs are mapped\, revealing variations in the consensus seque
 nces of the EPRV subgenera. These findings offer insights into the role of
  DICER2 and EPRV-derived 22nt sRNAs in plant viral immunity\, particularly
  in hybrid plants\, providing a foundation for further research. \n\n*Plea
 se note the seminars are for University Of Cambridge members ONLY.*
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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