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SUMMARY:Inositol Pyrophosphate Nutrient Signaling Networks In Plants - Mic
 hael Hothorn (University Of Geneva)
DTSTART:20241205T121500Z
DTEND:20241205T134500Z
UID:TALK219964@talks.cam.ac.uk
CONTACT:115405
DESCRIPTION:*Host* Prof. Uta Paszkowski\n\n*Abstract*\nInositol pyrophosph
 ates (PP-InsPs) are eukaryotic nutrient messengers with a well-established
  role in phosphate and nitrate homeostasis in plants. Their cellular conce
 ntration must be tightly regulated in response to changing nutrient condit
 ions. I will review our current understanding of PP-InsP synthesis and cat
 abolism in Arabidopsis and Marchantia polymorpha. I will then discuss at a
  mechanistic level how nutrients and energy metabolites regulate PP-InsP b
 iosynthesis and degradation. Using SPX receptor proteins as an example\, I
  will describe a three-component signalling pathway that enables PP-InsPs 
 to control plant phosphate homeostasis and starvation responses. Finally\,
  I will outline our current genetic and biochemical approaches to define n
 ovel receptors and physiological functions for these signalling molecules 
 in plants.\n\n*Biography*\nMichael studied Biology (Biochemistry/Biophysic
 s) at the University of Heidelberg\, Germany and did his PhD in structural
  biology at the European Molecular Biology Laboratory. After a postdoc wit
 h Joanne Chory at the Salk Institute\, he set up his independent research 
 group at the Friedrich Miescher Laboratory in Germany. In 2014 he became p
 rofessor at the Department of Plant Sciences at the University of Geneva.\
 n\n*Please note the seminars are for University Of Cambridge members ONLY.
 *
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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