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SUMMARY:Mechanism for Membrane Protein Insertion and Complex Assembly  - H
 aoxi Wu 
DTSTART:20241015T110000Z
DTEND:20241015T120000Z
UID:TALK220138@talks.cam.ac.uk
CONTACT:90994
DESCRIPTION:The human genome encodes approximately 5000 membrane proteins 
 of varied sizes\, shapes\, and biophysical properties. To function properl
 y\, most of these proteins need to be inserted into the membrane in the co
 rrect orientation\, folded into their three-dimensional structure\, and as
 sembled with partner proteins. How these membrane proteins are correctly m
 ade is not well understood. Using a biochemical approach to study factors 
 involved in membrane protein biogenesis\, I will discuss an emerging and u
 nifying model for membrane protein insertion and the identification and ch
 aracterization of assembly factors that facilitate complex formation.
LOCATION:Jean Thomas Lecture theatre\, Sanger Building\, Tennis Court Road
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