BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Tales of Traumatic Stress in High-Risk Populations in the Global S
 outh: From Epidemiological to Genomic and Epigenomic Insights - Professor 
 Soraya Seedat\,  Executive Head of the Department of Psychiatry at Stellen
 bosch University.
DTSTART:20241025T153000Z
DTEND:20241025T170000Z
UID:TALK220888@talks.cam.ac.uk
CONTACT:Sara Seddon
DESCRIPTION:Posttraumatic stress disorder (PTSD) is the quintessential dis
 order following high-violence exposure in low-resource contexts where time
 ly diagnosis and equitable access to evidence-based treatments are often l
 acking. While its genesis is multifactorial\, its presentation complex\, a
 nd often layered by concurrent mental and physical health conditions\, muc
 h progress has been made in identifying many of the underlying bio-behavio
 ural and environmental mechanisms\, and the influence of cultural factors\
 , in conferring relative risk or resilience\, and in developing and\n\nmai
 ntaining PTSD. However\, the vast majority of molecular and bio-mechanisti
 c studies in PTSD have been undertaken in high-income countries\, as well 
 as outside the African continent\, thus the current knowledge-base is far 
 from being reflective of the global burden of the disorder. This presentat
 ion\, with a focus on South Africa\, will elucidate the epidemiology of tr
 auma and the impact of childhood trauma in particular\, in various high-ri
 sk samples\, and the array of biological markers that have been identified
  and implicated in aberrant stress response processes in PTSD including ge
 notypic\, epigenetic\, transcriptomic\, endocrinological and immune marker
 s\, as well as sex-based contributors. I will argue that studies from dive
 rse low-and middle-income country populations can contribute important epi
 demiological and biological insights.
LOCATION:Ground Floor Lecture Theatre\, Department of  Psychology
END:VEVENT
END:VCALENDAR