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SUMMARY:Pulsating active systems - Alessandro Manacorda (Institute for Com
 plex Systems\, Rome)
DTSTART:20241004T143000Z
DTEND:20241004T150000Z
UID:TALK220966@talks.cam.ac.uk
DESCRIPTION:Deformation of single cells in biological tissues plays a stra
 tegic role in key processes such as stress propagation\, cardiac arrhytmia
 s and wound healing. The size and shape of a cell depends on its internal 
 cytoskeletal activity and nearest-neighbors interactions in a dense enviro
 nment. Size synchronization and contraction waves emerge as collective beh
 avior typical of non-equilibrium systems.\nWe introduce pulsating active m
 atter (PAM) as a physical framework to model these scenarios and provide t
 he minimal ingredients to observe the non-equilibrium phases mentioned. Ac
 tivity in PAM does not enter as a classical self-propulsion mechanism but 
 rather as a non-equilibrium dynamics of the degrees of freedom controlling
  the cells' shape. These assumptions lead to collective dynamics\, which c
 an be analysed through a coarse-grained hydrodynamic approach. We elucidat
 e the role of density and size fluctuations and the general mechanisms yie
 lding the transitions described. PAM provides then a framework to tackle e
 merging challenges in the collective behavior of deformable units.\nCo-Aut
 hors: &Eacute\;tienne Fodor\, Yiwei Zhang\, Luca Casagrande\nReferences: Y
 . Zhang and &Eacute\;. Fodor\, Pulsating Active Matter\, Phys. Rev. Lett. 
 131\, 238302 \; A. Manacorda and &Eacute\;. Fodor\, Pulsating with Discret
 e Symmetry\, arXiv:2310.14370
LOCATION:Seminar Room 1\, Newton Institute
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