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SUMMARY:Placental macrophages and how they fight Listeria monocytogenes in
 fection. - Dr Naomi McGovern\, Department of Pathology &amp\; Centre for T
 rophoblast Research\, Cambridge
DTSTART:20241003T150000Z
DTEND:20241003T160000Z
UID:TALK220987@talks.cam.ac.uk
CONTACT:Ruth Paton
DESCRIPTION:This Cambridge Immunology Network Seminar will take place on T
 hursday 3 October 2024\, starting at 4:00pm\, in the Ground Floor Lecture 
 Theatre\, Jeffrey Cheah Biomedical Centre (JCBC)\n\nSpeaker: Dr Naomi McGo
 vern\, Department of Pathology & Centre for Trophoblast Research\, Cambrid
 ge\n\nTitle: Placental macrophages and how they fight Listeria monocytogen
 es infection.\n\n\nListeriosis is a foodborne disease caused by Listeria m
 onocytogenes\, a Gram-positive bacterium that is ubiquitous in the environ
 ment. Listeriosis generally causes mild-to-moderate clinical symptoms of g
 astroenteritis. However\, if it crosses the placenta\, fetal infection can
  have devastating sequelae\, including neonatal sepsis and neurodevelopmen
 tal delay.\n\nThe human placenta contains one population of immune cells\,
  macrophages known as Hofbauer cells. Here\, we describe how their propert
 ies change across gestation and the impact of these changes on their inter
 actions with Listeria monocytogenes.\n\nHost: Patrycja Kozik\, PNAC Divisi
 on\, MRC-LMB\, University of Cambridge\n\nRefreshments will be available f
 ollowing the Seminar.
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
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