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SUMMARY:Generative modelling for de novo design of therapeutics - Dr Joe W
 atson - Co-founder\, Xaira Therapeutics and Dr Emile Mathieu
DTSTART:20250305T150500Z
DTEND:20250305T155500Z
UID:TALK223297@talks.cam.ac.uk
CONTACT:Ben Karniely
DESCRIPTION:Generative models have emerged as a powerful tool for capturin
 g biology. In the field of protein design\, generative models have recentl
 y brought previously challenging problems within reach\, such as protein m
 onomer design\, motif scaffolding\, and de novo interface design. The de n
 ovo design of therapeutics however\, is a more challenging problem\, which
  still remains unsolved. \nAntibodies are the largest current class of the
 rapeutics. Their biocompatibility and specificity renders them well-suited
  for the treatment of a broad range of conditions. However\, their rationa
 l design has proved challenging\, due to data limitations and their harder
 -to-model interfaces.\n\nIn this talk\, we set out a roadmap towards solvi
 ng therapeutic antibody design. We will leverage previous work to motivate
  this path\, and survey recent developments in the field of generative mod
 eling that we believe are relevant for this task.\n\n\nLink to join virtua
 lly: https://cam-ac-uk.zoom.us/j/87421957265\n\nThis talk is not being rec
 orded\n\n
LOCATION:Lecture Theatre 1\, Computer Laboratory\, William Gates Building
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