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SUMMARY:Dopamine signalling in the octopus visual system - Anna Jansson\, 
 Cambridge -- Translational Neuroscience
DTSTART:20241024T120000Z
DTEND:20241024T130000Z
UID:TALK223411@talks.cam.ac.uk
CONTACT:Alexander R Epstein
DESCRIPTION:Octopuses are an emerging model organism in neurobiology given
  their capacity for intelligence and unique nervous systems. However\, due
  to this novelty\, nothing is currently known about most of the chemical s
 ignalling between their neurons. Given the historical significance of mono
 amine neurotransmitters (dopamine\, serotonin\, norepinephrine\, epinephri
 ne\, etc.) in mammalian brains\, combined with knowledge of serotonin sign
 aling for octopus camouflage and the identification of prolific dopamine s
 ynthesis in their visual system\, we chose to explore monoamine G-protein 
 coupled receptors (GPCRs) in Octopus vulgaris. We identified two dopamine\
 , two serotonin\, and two norepinephrine GPCRs\, five of which we localise
 d in the infant octopus brain. These results allow us to generate new hypo
 theses regarding the integration of monoamine receptors with other neurotr
 ansmission\, especially relating to their use in processing visual informa
 tion.
LOCATION:Richard King room\, Darwin College
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