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SUMMARY:“Imaging the Immune System in Tissue Repair” - Professor Paul 
 Kubes\, Cumming School of Medicine\, University of Calgary
DTSTART:20250508T150000Z
DTEND:20250508T160000Z
UID:TALK225433@talks.cam.ac.uk
CONTACT:Ruth Paton
DESCRIPTION:This Cambridge Immunology and Medicine Seminar will take place
  on Thursday 8 May 2025\, starting at 4:00pm\, in the Ground Floor Lecture
  Theatre\, Jeffrey Cheah Biomedical Centre (JCBC)\n\nSpeaker: Professor Pa
 ul Kubes\, Cumming School of Medicine\, University of Calgary\n\nTitle: 
 “Imaging the Immune System in Tissue Repair”\n\nAbstract: Using a very
  simple model of tissue injury where a thermal probe is touched to the sur
 face of a tissue and kills about 1000 cells has unveiled a very complex se
 ries of immune events that lead to complete repair in tissues like the liv
 er.  Neutrophils enter the site\, clear the debris and leave again via th
 e vasculature while monocytes and iNKT cells surround the injury and slowl
 y the monocytes convert to a repair phenotype before entering and working 
 with stellate cells to help to return the structure back to homeostasis. 
  The outer compartment where the mesothelium has to regrow requires that p
 eritoneal macrophages attach to the injury site take on a repair phenotype
  with the help of peritoneal mast cells and aid in repair. Some of these s
 ame principles apply to chronic injury  and cancer. \n\nHost: Tim Halim\
 , CRUK Cambridge\n\nRefreshments will be available following the seminar.
LOCATION: Lecture Theatre\, Jeffrey Cheah Biomedical Centre\, Cambridge Bi
 omedical Campus
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