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SUMMARY:Deciphering how complex organ form emerges in development  - Timot
 hy Saunders
DTSTART:20250303T143000Z
DTEND:20250303T153000Z
UID:TALK225514@talks.cam.ac.uk
CONTACT:Jia CHEN
DESCRIPTION:Abstract: Our internal organs have specific three-dimensional 
 morphologies essential for their efficient function. Defects in morphogene
 sis lead to diseases in adults – for example\, over 40% of adult heart d
 isease can be traced to a developmental context. Yet\, we know remarkably 
 little about the physical processes underlying internal organ morphogenesi
 s. Here\, I present quantitative analysis of early muscle formation in zeb
 rafish. This system is highly accessibly to live imaging and is enabling u
 s to decipher the biophysical mechanisms helping to build the first skelet
 al muscle structures. In particular\, we explore how organogenesis can be 
 so robust in the face of challenges during development. 
LOCATION:in person at Sainsbury Laboratory and online
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