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SUMMARY:LMB Seminar - Ribosome Upside Down: Co-translational Protein Bioge
 nesis at the Tunnel Exit - In person only - Nenad Ban - ETH Zürich
DTSTART:20250917T100000Z
DTEND:20250917T110000Z
UID:TALK225739@talks.cam.ac.uk
CONTACT:Scientific Meetings Co-ordinator
DESCRIPTION:Our group aims to understand the cellular mechanisms underlyin
 g the production of functional proteins. This complex process requires an 
 intricate interplay between the ribosome and a growing number of cellular 
 factors that regulate translation and co-translational protein biogenesis.
  One of the key topics of our research\, which combines structural\, bioch
 emical\, and biophysical approaches\, is the biogenesis of cytosolic and m
 embrane proteins controlled by the nascent polypeptide–associated comple
 x (NAC). I will present recent results that reveal how NAC coordinates the
  activity of a network of factors and enzymes at translating ribosomes to 
 facilitate virtually all aspects of protein biogenesis\, including nascent
  chain processing\, modification\, folding\, and cellular localization suc
 h as targeting to the ER.\n\n
LOCATION:In person in the Max Perutz Lecture Theatre (CB2 0QH) 
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