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SUMMARY:The bacterial pathogen Xanthomonas citri repurposes a fruit ripeni
 ng programme to gain access to cell wall-bound carbohydrates.  - Thomas La
 haye (University of Tübingen\, Baden-Württemberg\, Germany)
DTSTART:20250313T121500Z
DTEND:20250313T134500Z
UID:TALK225940@talks.cam.ac.uk
CONTACT:115405
DESCRIPTION:*Host* Prof. Sebastian Schornack\n\n*Abstract* Virulence of _X
 anthomonas citri_ ssp. _citri_ (Xcc) depends on the transcription activato
 r-like effector PthA4\, which activates the host transcription factor CsLO
 B1. To elucidate how CsLOB1 promotes Xcc\, we integrated RNA-seq and ChIP-
 seq data and identified 96 CsLOB1-activated genes containing a CsLOB1 bind
 ing site\, many encoding cell wall (CW) degrading enzymes (CWDEs). We pred
 icted a CsLOB1 target motif and found that promoters containing this motif
  are activated by both CsLOB1 and the tomato ortholog SlLOB1\, which is ex
 pressed exclusively at the onset of fruit ripening. We found that CsLOB1 i
 s also expressed at the onset of ripening\, suggesting that PthA4 hijacks 
 the ripening programme to activate CWDEs and access plant CW sugars. \n\n*
 Biography* During my PhD\, I worked on cloning components of powdery milde
 w resistance in barley (Sainsbury Lab\, Norwich\; UK). From my first postd
 oc (University of Halle\, Germany) to the present day (University of Tübi
 ngen\, Germany)\, I have been working on effector proteins of the bacteria
 l plant pathogen Xanthomonas\, trying to understand how effectors increase
  the susceptibility of the host plant or trigger immune responses. \n\n*Pl
 ease note the seminars are for University Of Cambridge members ONLY.*
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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