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SUMMARY:Structural and molecular basis of DNA transfer by bacterial conjug
 ative systems - Gabriel Waksman 
DTSTART:20250610T110000Z
DTEND:20250610T120000Z
UID:TALK226480@talks.cam.ac.uk
CONTACT:90994
DESCRIPTION:Bacterial conjugation is the unidirectional transport of genet
 ic materials from a donor to a recipient cell. It plays crucial roles in b
 acterial evolution and adaptation. It is also the principal means by which
  antibiotic resistance genes spread among bacterial populations. It is med
 iated in the donor cell by three major complexes that work in concert: a D
 NA-processing machinery called the relaxosome\, a double-membrane spanning
  transfer machinery termed type 4 secretion system (T4SS)\, and an extrace
 llular appendage termed pilus. For this seminar\, focus will be on the rec
 ent structures we have determined\, notably that of the relaxosome.
LOCATION:Jean Thomas Lecture theatre\, Sanger Building\, Tennis Court Road
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