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SUMMARY:A telomeric tale: 2500 years of human betaherpesvirus evolution - 
  Dr Charlotte Houldcroft\, Department of Genetics
DTSTART:20250225T130000Z
DTEND:20250225T140000Z
UID:TALK228823@talks.cam.ac.uk
CONTACT:Henry North
DESCRIPTION:Human betaherpesviruses 6A and 6B are double-stranded DNA viru
 ses carried by large fractions of the human population and integrate into 
 the human genome\, leading to a wide range of clinical manifestations such
  as angina and pre-eclampsia. Despite only being discovered in the 1980s\,
  these viruses are speculated to have a much longer history within the hum
 an population than modern data make clear. In this talk\, I will present t
 he first nine full and two partial ancient genomes of HHV-6A and 6B\, dati
 ng as far back as the Italian Iron Age. We demonstrate that large fraction
 s of current HHV-6 diversity were already well established in the human po
 pulation by the 14th century CE\, and likely much earlier.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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