BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:A tale of two algorithms: Structured slots explain prefrontal sequ
 ence memory and are unified with hippocampal cognitive maps - Ece Bilgic
DTSTART:20250226T150000Z
DTEND:20250226T160000Z
UID:TALK228973@talks.cam.ac.uk
CONTACT:Adam Triabhall
DESCRIPTION:This week we will discuss and debate a very recent paper by Wh
 ittington and colleagues (2025).\n\nAbstract: “Remembering events is cru
 cial to intelligent behavior. Flexible memory retrieval requires a cogniti
 ve map and is supported by two key brain systems: hippocampal episodic mem
 ory (EM) and prefrontal working memory (WM). Although an understanding of 
 EM is emerging\, little is understood of WM beyond simple memory retrieval
 . We develop a mathematical theory relating the algorithms and representat
 ions of EM and WM by unveiling a duality between storing memories in synap
 ses versus neural activity. This results in a formalism of prefrontal WM a
 s structured\, controllable neural subspaces (activity slots) representing
  dynamic cognitive maps without synaptic plasticity. Using neural networks
 \, we elucidate differences\, similarities\, and trade-offs between the hi
 ppocampal and prefrontal algorithms. Lastly\, we show that prefrontal repr
 esentations in tasks from list learning to cue-dependent recall are unifie
 d as controllable activity slots. Our results unify frontal and temporal r
 epresentations of memory and offer a new understanding for dynamic prefron
 tal representations of WM” (Whittington et al.\, 2025).\n\nReference:  W
 hittington\, J. C. R.\, Dorrell\, W.\, Behrens\, T. E. J.\, Ganguli\, S & 
 El-Gaby\, M. (2025). A tale of two algorithms: Structured slots explain pr
 efrontal sequence memory and are unified with hippocampal cognitive maps. 
 Neuron\, 113(2). https://doi.org/10.1016/j.neuron.2024.10.017
LOCATION:https://cam-ac-uk.zoom.us/j/92612577704?pwd=MUtqMjVQdXNmUTVIYjRkM
 G1NUW9GZz09
END:VEVENT
END:VCALENDAR