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SUMMARY:A short and personal history of planar cell polarity - Peter A. La
 wrence - Department of Zoology
DTSTART:20250402T150000Z
DTEND:20250402T163000Z
UID:TALK229270@talks.cam.ac.uk
CONTACT:Daniel Sobrido-Cameán
DESCRIPTION:Its about 30 years since we started to research planar cell po
 larity\, a small defined field with its feet in genetics and its head in t
 heory. How do cells orient themselves in the whole\, how do they align the
  little structures such as subcellular denticles of insects or the multice
 llular hairs of a mammal\, how do they know which way to send out an axon\
 , which way to point a nascent arm? When we started the field was intrigui
 ng\, fashionable. Now it remains important and interesting but is rusty an
 d largely abandoned. Most scientists who worked in the field have moved on
 \, leaving many problems unsolved. We (and others) used fly genetics. We s
 ummarise some principles of mechanism that we discovered with genetic mosa
 ics.
LOCATION:Max Perutz Lecture Theatre. LMB. Cambridge.
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